From 2021 through 2025, federal agencies obligated $5.95 billion across 2,997 award actions in NAICS 541711, with an average action value of $1.98 million. The Department of Energy accounts for most obligated dollars, while HHS preparedness, NIH, FDA, and procurement operations make up much of the remaining activity by award count and value.
NAICS Industry
NAICS 541711 Federal Contract Obligations (Last 5 Years)
FPDS procurement data for NAICS 541711 shows federal obligations for biotechnology research and development over the last 5 years.
Annual obligations peaked in 2023 at $1.74 billion and were lowest in 2025 at $477.85 million, based on readable FPDS data.
NAICS Code
541711
Industry
RESEARCH AND DEVELOPMENT IN BIOTECHNOLOGY
Total Obligated
5.95 billion
5,947,286,944.88
Award Actions
2,997
Average Action Value
1,984,413.39
About NAICS 541711 federal contract activity
NAICS 541711 covers research and development in biotechnology and represents 5.95 billion in obligated federal spending across 2,997 awards over the last 5 years. The average award value was 1.98 million, indicating a mix of large, mission-driven R&D contracts and a high volume of smaller obligations.
Agency demand and leading federal buyers
The Department of Energy dominates federal spending in this NAICS, accounting for 4.79 billion across 223 awards, or the clear majority of obligated dollars. The next largest buyers by obligation were the Office of Assistant Secretary for Preparedness and Response at 804.94 million and the National Institutes of Health at 217.92 million, showing that biotechnology R&D demand is concentrated in energy, public health preparedness, and biomedical research agencies.
Vendor concentration and leading contractors
Alliance for Sustainable Energy, LLC is the primary recipient by a wide margin, with 4.79 billion obligated across 223 awards. The remaining top vendors are much smaller in scale, led by Emergent Product Development Gaithersburg Inc. at 679.21 million and followed by Cerus Corporation, American Type Culture Collection, and Hoffmann-La Roche Inc., indicating a steep drop-off after the leading contractor.
Annual contract trend over the analysis window
Annual obligations peaked in 2023 at 1.74 billion, then declined to 1.33 billion in 2024 and 477.85 million in 2025. Award counts were highest in 2021 at 930 and then fell each year to 221 in 2025, suggesting a contraction in both transaction volume and spending after the 2021-2023 period.
How to interpret this page
This page summarizes FPDS obligations for NAICS 541711 over the last 5 years using total obligated dollars, award counts, and average award value. Agency and vendor rankings are based on total obligated amount, and annual trend values reflect obligations recorded in each fiscal year within the analysis window.
Top Agencies
SELECT
agency_id,
agency_name,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
content__award__purchaserInformation__contractingOfficeAgencyID AS agency_id,
anyHeavy(content__award__purchaserInformation__contractingOfficeAgencyID__name) AS agency_name,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '541711'
AND content__award__purchaserInformation__contractingOfficeAgencyID IS NOT NULL
AND content__award__purchaserInformation__contractingOfficeAgencyID != ''
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 5 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY agency_id
)
ORDER BY total_obligated DESC
LIMIT 10| Agency ID | Agency Name | Total Obligated | Readable | Award Actions |
|---|---|---|---|---|
| 8900 | ENERGY, DEPARTMENT OF | 4,787,916,142.91 | 4.79 billion | 223 |
| 7505 | OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE | 804,940,540.65 | 804.94 million | 531 |
| 7529 | NATIONAL INSTITUTES OF HEALTH | 217,923,757.50 | 217.92 million | 1,412 |
| 7001 | OFFICE OF PROCUREMENT OPERATIONS | 57,916,413.08 | 57.92 million | 155 |
| 7524 | FOOD AND DRUG ADMINISTRATION | 28,361,586.21 | 28.36 million | 150 |
| 2100 | DEPT OF THE ARMY | 22,373,124.96 | 22.37 million | 191 |
| 5700 | DEPT OF THE AIR FORCE | 13,006,633.00 | 13.01 million | 29 |
| 97DH | DEFENSE HEALTH AGENCY (DHA) | 6,110,127.00 | 6.11 million | 9 |
| 9761 | DEFENSE THREAT REDUCTION AGENCY (DTRA) | 4,611,166.64 | 4.61 million | 44 |
| 7523 | CENTERS FOR DISEASE CONTROL AND PREVENTION | 4,524,701.95 | 4.52 million | 63 |
Insight
Over the last 5 years, NAICS 541711 shows a highly concentrated obligation profile, with the Department of Energy accounting for $4.79 billion of the $5.95 billion total, or roughly 80 percent, across 223 awards. The Office of Assistant Secretary for Preparedness and Response and the National Institutes of Health provide the next largest shares at $804.94 million and $217.92 million, respectively, indicating that federal demand is concentrated in a small number of health- and science-related agencies. Outside the top three, obligations drop sharply, with each remaining agency at less than $60 million, while award counts are more dispersed, especially at NIH with 1,412 awards versus comparatively few high-dollar awards at DOE.
Top Vendors
SELECT
vendor_name,
cage_code,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
content__award__vendor__vendorHeader__vendorName AS vendor_name,
anyHeavy(content__award__vendor__vendorSiteDetails__entityIdentifiers__cageCode) AS cage_code,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '541711'
AND content__award__vendor__vendorHeader__vendorName IS NOT NULL
AND content__award__vendor__vendorHeader__vendorName != ''
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 5 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY vendor_name
)
ORDER BY total_obligated DESC
LIMIT 10| Vendor | CAGE Code | Total Obligated | Readable | Award Actions |
|---|---|---|---|---|
| ALLIANCE FOR SUSTAINABLE ENERGY, LLC | 50B53 | 4,787,916,142.91 | 4.79 billion | 223 |
| EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. | 057Y1 | 679,212,387.59 | 679.21 million | 28 |
| CERUS CORPORATION | 1PVJ6 | 68,520,127.00 | 68.52 million | 18 |
| AMERICAN TYPE CULTURE COLLECTION | 31101 | 63,340,607.71 | 63.34 million | 25 |
| HOFFMANN-LA ROCHE INC. | 04493 | 62,580,073.86 | 62.58 million | 11 |
| BATTELLE NATIONAL BIODEFENSE INSTITUTE, LLC | 4MUX2 | 57,916,068.02 | 57.92 million | 127 |
| EMMES CORPORATION, THE | 3EX59 | 35,276,965.89 | 35.28 million | 30 |
| MERCK SHARP & DOHME CORP. | 6B2S4 | 32,680,532.19 | 32.68 million | 7 |
| MEDICINES COMPANY, THE | 37CG9 | 31,144,230.00 | 31.14 million | 6 |
| BATTELLE MEMORIAL INSTITUTE | 79986 | 21,815,606.23 | 21.82 million | 228 |
Insight
Obligations in NAICS 541711 are highly concentrated over the last 5 years: ALLIANCE FOR SUSTAINABLE ENERGY, LLC accounted for 4.79 billion of 5.95 billion total obligated, or about 80.5%, across 223 awards. The remaining top vendors each represent a much smaller share, with only EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. exceeding 679.21 million; most others are below 70 million. Award volume is more distributed than dollars, as several vendors have relatively high award counts but materially lower obligated values, indicating a skew toward a single dominant recipient.
Annual Trend
SELECT
year,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
toYear(parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate)) AS year,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '541711'
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 5 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY year
)
ORDER BY year DESC| Year | Total Obligated | Readable | Award Actions |
|---|---|---|---|
| 2025 | 477,846,628.42 | 477.85 million | 221 |
| 2024 | 1,334,102,391.25 | 1.33 billion | 506 |
| 2023 | 1,736,098,102.02 | 1.74 billion | 567 |
| 2022 | 1,098,498,332.78 | 1.10 billion | 773 |
| 2021 | 1,300,741,490.41 | 1.30 billion | 930 |
Insight
Over the last 5 years, NAICS 541711 has obligated $5.95 billion across 2,997 awards, with an average award value of $1.98 million. Obligations peaked in 2023 at $1.74 billion, then declined to $1.33 billion in 2024 and $477.85 million in 2025, indicating a recent contraction after a high-spend year. Award volume also fell from 930 in 2021 to 221 in 2025, while 2022 and 2023 sustained higher obligation levels with fewer awards than 2021, suggesting a shift toward fewer, larger awards during the middle of the period.
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