Federal spending under NAICS 325414 totaled $27.41 billion across 10,942 award actions, with an average action value of $2.51 million. The activity is concentrated in the Department of the Army and a small group of vaccine and biologics manufacturers, led by Pfizer, Regeneron, and Moderna.
NAICS Industry
NAICS 325414 Federal Contract Obligations (Last 10 Years)
NAICS 325414 covers federal obligations for biological product manufacturing, excluding diagnostics, over the last 10 years.
Annual totals include negative obligations in some years, which can reflect deobligations or contract adjustments in FPDS.
NAICS Code
325414
Industry
BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING
Total Obligated
27.41 billion
27,413,773,031.85
Award Actions
10,942
Average Action Value
2,505,371.32
About NAICS 325414 federal contract activity
NAICS 325414, Biological Product (Except Diagnostic) Manufacturing, recorded 27.41 billion in obligated spending across 10,942 awards over the last 10 years, with an average award value of 2.51 million. The obligation profile is highly concentrated, indicating that a relatively small number of large transactions account for a substantial share of total spend.
Agency demand and leading federal buyers
The Department of the Army led all agencies by a wide margin with 20.84 billion obligated across 268 awards, far exceeding the next-largest buyer. Office of Assistant Secretary for Preparedness and Response and the Centers for Disease Control and Prevention were the next largest contributors at 4.31 billion and 1.42 billion respectively, while the remaining top agencies were materially smaller, including Defense Logistics Agency and Animal and Plant Health Inspection Service.
Vendor concentration and leading contractors
PFIZER INC. dominated vendor activity with 15.26 billion obligated across 61 awards, representing the largest share of spending in the category. REGENERON PHARMACEUTICALS, INC. followed at 5.57 billion, while MODERNATX, INC., SANOFI PASTEUR INC., and EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. also appear among the leading recipients, with award counts showing that high obligation totals do not always align with high transaction volume.
Annual contract trend over the analysis window
Annual obligations were volatile over the most recent five-year slice, with 2021 standing out at 20.45 billion and 1,054 awards. Obligations fell sharply in 2022 to -281.57 million, rebounded in 2023 and 2024 to 307.51 million and 918.89 million, and were slightly negative in 2025 at -7.55 million; award counts remained elevated throughout, ranging from 491 to 1,054.
How to interpret this page
This page summarizes FPDS obligations reported under NAICS 325414 for the last 10 years and aggregates them by agency, vendor, and fiscal year. Negative annual totals reflect deobligations or adjustments in the source data and are presented as reported.
Top Agencies
SELECT
agency_id,
agency_name,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
content__award__purchaserInformation__contractingOfficeAgencyID AS agency_id,
anyHeavy(content__award__purchaserInformation__contractingOfficeAgencyID__name) AS agency_name,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '325414'
AND content__award__purchaserInformation__contractingOfficeAgencyID IS NOT NULL
AND content__award__purchaserInformation__contractingOfficeAgencyID != ''
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 10 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY agency_id
)
ORDER BY total_obligated DESC
LIMIT 10| Agency ID | Agency Name | Total Obligated | Readable | Award Actions |
|---|---|---|---|---|
| 2100 | DEPT OF THE ARMY | 20,835,869,220.24 | 20.84 billion | 268 |
| 7505 | OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE | 4,309,580,367.48 | 4.31 billion | 716 |
| 7523 | CENTERS FOR DISEASE CONTROL AND PREVENTION | 1,417,053,689.39 | 1.42 billion | 594 |
| 97AS | DEFENSE LOGISTICS AGENCY | 344,406,351.20 | 344.41 million | 562 |
| 12K3 | ANIMAL AND PLANT HEALTH INSPECTION SERVICE | 199,724,053.85 | 199.72 million | 216 |
| 7529 | NATIONAL INSTITUTES OF HEALTH | 146,636,875.18 | 146.64 million | 6,615 |
| 3600 | VETERANS AFFAIRS, DEPARTMENT OF | 86,326,305.29 | 86.33 million | 639 |
| 7524 | FOOD AND DRUG ADMINISTRATION | 17,582,159.29 | 17.58 million | 292 |
| 1700 | DEPT OF THE NAVY | 13,541,996.61 | 13.54 million | 199 |
| 97DH | DEFENSE HEALTH AGENCY (DHA) | 12,147,869.95 | 12.15 million | 124 |
Insight
Over the last 10 years, obligations under NAICS 325414 total $27.41 billion across 10,942 awards, with spending highly concentrated in a few agencies. The Department of the Army accounts for $20.84 billion, or about 76% of total obligations, far exceeding all other agencies; the Office of Assistant Secretary for Preparedness and Response and CDC follow at $4.31 billion and $1.42 billion, respectively. Award volume is more dispersed than dollars: NIH has 6,615 awards but only $146.64 million obligated, indicating a large number of relatively small awards outside the top dollar spenders.
Top Vendors
SELECT
vendor_name,
cage_code,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
content__award__vendor__vendorHeader__vendorName AS vendor_name,
anyHeavy(content__award__vendor__vendorSiteDetails__entityIdentifiers__cageCode) AS cage_code,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '325414'
AND content__award__vendor__vendorHeader__vendorName IS NOT NULL
AND content__award__vendor__vendorHeader__vendorName != ''
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 10 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY vendor_name
)
ORDER BY total_obligated DESC
LIMIT 10| Vendor | CAGE Code | Total Obligated | Readable | Award Actions |
|---|---|---|---|---|
| PFIZER INC. | 86491 | 15,260,969,165.68 | 15.26 billion | 61 |
| REGENERON PHARMACEUTICALS, INC. | 544P9 | 5,565,000,000.00 | 5.57 billion | 8 |
| MODERNATX, INC. | 6RP85 | 1,754,345,480.45 | 1.75 billion | 24 |
| SANOFI PASTEUR INC. | 7V915 | 836,671,625.15 | 836.67 million | 242 |
| EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. | 057Y1 | 817,086,207.46 | 817.09 million | 16 |
| EMERGENT BIODEFENSE OPERATIONS LANSING LLC | 1H0B6 | 781,249,420.32 | 781.25 million | 44 |
| ADVANCED TECHNOLOGY INTERNATIONAL | 1G3V8 | 686,499,782.02 | 686.50 million | 43 |
| VALNEVA USA, INC. | 43FM1 | 196,576,724.80 | 196.58 million | 26 |
| AMGEN USA INC. | 5YNZ4 | 192,762,861.33 | 192.76 million | 10 |
| GLAXOSMITHKLINE LLC | 667E9 | 167,125,377.40 | 167.13 million | 89 |
Insight
Over the last 10 years, NAICS 325414 accounts for $27.41 billion across 10,942 awards, with an average award value of $2.51 million. Obligations are highly concentrated: Pfizer Inc. received $15.26 billion, or more than half of total obligations, and the top three vendors together account for roughly 85 percent of obligated dollars. The remaining top vendors each received less than $1 billion, indicating a steep drop-off after the leading firms and a highly skewed award distribution.
Annual Trend
SELECT
year,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
toYear(parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate)) AS year,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '325414'
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 10 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY year
)
ORDER BY year DESC| Year | Total Obligated | Readable | Award Actions |
|---|---|---|---|
| 2025 | -7,549,242.46 | -7.55 million | 491 |
| 2024 | 918,887,389.17 | 918.89 million | 811 |
| 2023 | 307,512,762.42 | 307.51 million | 830 |
| 2022 | -281,571,030.07 | -281.57 million | 1,008 |
| 2021 | 20,447,867,572.99 | 20.45 billion | 1,054 |
| 2020 | 3,505,849,455.41 | 3.51 billion | 950 |
| 2019 | 518,029,601.41 | 518.03 million | 929 |
| 2018 | 369,458,533.02 | 369.46 million | 1,376 |
| 2017 | 1,033,315,255.67 | 1.03 billion | 1,815 |
| 2016 | 601,972,734.29 | 601.97 million | 1,678 |
Insight
NAICS 325414 shows a highly concentrated obligation profile over the last 10 years, with 2021 accounting for 20.45 billion of the 27.41 billion total obligated, or roughly three-quarters of all dollars. Annual obligations were much lower before and after that peak, generally ranging from about 369.46 million to 3.51 billion, with negative obligations in 2022 (-281.57 million) and 2025 (-7.55 million) indicating net deobligations in those years. Award volume was spread more evenly than dollars, with annual counts ranging from 491 in 2025 to 1,815 in 2017, suggesting that obligation value is more volatile than award count.
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