This NAICS page summarizes federal awards for biological product manufacturing, excluding diagnostics, showing a market dominated by the Department of the Army and major obligations to Pfizer Inc. and Regeneron Pharmaceuticals, Inc. Annual activity was highest in 2021 and remained substantial through 2024, with 2025 showing a small net deobligation.
NAICS Industry
NAICS 325414 Federal Contract Obligations (Last 5 Years)
Federal procurement activity for NAICS 325414 covers biological product manufacturing, excluding diagnostics, with $21.39 billion obligated across 4,194 actions in the last 5 years.
Totals are based on the last 5 years of readable FPDS obligations and may include deobligations, so annual totals can be negative.
NAICS Code
325414
Industry
BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING
Total Obligated
21.39 billion
21,385,147,452.05
Award Actions
4,194
Average Action Value
5,098,986.04
About NAICS 325414 federal contract activity
Over the last 5 years, FPDS records for NAICS 325414, Biological Product (except Diagnostic) Manufacturing, show $21.39 billion in obligated contract value across 4,194 awards, with an average award value of $5.10 million. The category is heavily concentrated in a small number of high-dollar awards, indicating a market shaped by a few large procurement actions rather than broad-based purchasing.
Agency demand and leading federal buyers
The Department of the Army is the dominant buyer in this NAICS, accounting for $18.82 billion across 129 awards, or the vast majority of total obligated value. The Administration for Strategic Preparedness and Response is a distant second at $2.08 billion, while the Defense Logistics Agency, Animal and Plant Health Inspection Service, and National Institutes of Health contribute materially smaller shares of spending.
Vendor concentration and leading contractors
PFIZER INC. is the largest vendor by a wide margin, with $13.25 billion obligated across 59 awards, followed by REGENERON PHARMACEUTICALS, INC. at $5.57 billion across 8 awards. MODERNATX, INC., ADVANCED TECHNOLOGY INTERNATIONAL, and EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. round out the top vendors, reflecting a vendor base dominated by a few major biological product suppliers.
Annual contract trend over the analysis window
Annual obligations were highly uneven over the period, led by 2021 at $20.45 billion and followed by a sharp decline in 2022 and 2023. Spending rebounded in 2024 to $918.89 million, while 2025 shows a modest net negative obligated value of $7.55 million to date, suggesting ongoing deobligations or adjustments in current-year records.
How to interpret this page
This summary is based on FPDS obligations classified under NAICS 325414 over the last 5 years, using total obligated dollars, award counts, and year-by-year trends. Negative annual totals are retained as reported in FPDS and typically reflect deobligations, modifications, or other downward adjustments rather than new award activity.
Top Agencies
SELECT
agency_id,
agency_name,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
content__award__purchaserInformation__contractingOfficeAgencyID AS agency_id,
anyHeavy(content__award__purchaserInformation__contractingOfficeAgencyID__name) AS agency_name,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '325414'
AND content__award__purchaserInformation__contractingOfficeAgencyID IS NOT NULL
AND content__award__purchaserInformation__contractingOfficeAgencyID != ''
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 5 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY agency_id
)
ORDER BY total_obligated DESC
LIMIT 10| Agency ID | Agency Name | Total Obligated | Readable | Award Actions |
|---|---|---|---|---|
| 2100 | DEPT OF THE ARMY | 18,819,332,400.84 | 18.82 billion | 129 |
| 7505 | ADMINISTRATION FOR STRATEGIC PREPAREDNESS AND RESPONSE | 2,079,495,656.93 | 2.08 billion | 325 |
| 97AS | DEFENSE LOGISTICS AGENCY | 215,107,741.18 | 215.11 million | 243 |
| 12K3 | ANIMAL AND PLANT HEALTH INSPECTION SERVICE | 119,412,743.88 | 119.41 million | 99 |
| 7529 | NATIONAL INSTITUTES OF HEALTH | 67,542,217.71 | 67.54 million | 2,378 |
| 3600 | VETERANS AFFAIRS, DEPARTMENT OF | 43,913,684.73 | 43.91 million | 347 |
| 97DH | DEFENSE HEALTH AGENCY (DHA) | 11,484,577.53 | 11.48 million | 106 |
| 7524 | FOOD AND DRUG ADMINISTRATION | 5,879,211.20 | 5.88 million | 107 |
| 7523 | CENTERS FOR DISEASE CONTROL AND PREVENTION | 5,640,803.53 | 5.64 million | 180 |
| 7570 | OFFICE OF THE ASSISTANT SECRETARY FOR ADMINISTRATION (ASA) | 3,684,597.39 | 3.68 million | 7 |
Insight
Over the last 5 years, NAICS 325414 obligations total $21.39 billion across 4,194 awards, with average award value of about $5.10 million. Spending is highly concentrated: the Department of the Army accounts for $18.82 billion, or roughly 88% of total obligated dollars, followed by the Administration for Strategic Preparedness and Response at $2.08 billion; the remaining top agencies are each below $216 million. Award volume is more dispersed than dollars, with NIH leading the listed agencies by award count at 2,378 awards despite only $67.54 million obligated.
Top Vendors
SELECT
vendor_name,
cage_code,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
content__award__vendor__vendorHeader__vendorName AS vendor_name,
anyHeavy(content__award__vendor__vendorSiteDetails__entityIdentifiers__cageCode) AS cage_code,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '325414'
AND content__award__vendor__vendorHeader__vendorName IS NOT NULL
AND content__award__vendor__vendorHeader__vendorName != ''
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 5 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY vendor_name
)
ORDER BY total_obligated DESC
LIMIT 10| Vendor | CAGE Code | Total Obligated | Readable | Award Actions |
|---|---|---|---|---|
| PFIZER INC. | 86491 | 13,249,686,665.68 | 13.25 billion | 59 |
| REGENERON PHARMACEUTICALS, INC. | 544P9 | 5,565,000,000.00 | 5.57 billion | 8 |
| MODERNATX, INC. | 6RP85 | 799,450,501.45 | 799.45 million | 19 |
| ADVANCED TECHNOLOGY INTERNATIONAL | 1G3V8 | 686,499,782.02 | 686.50 million | 43 |
| EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. | 057Y1 | 458,576,057.46 | 458.58 million | 12 |
| VALNEVA USA, INC. | 43FM1 | 108,743,700.80 | 108.74 million | 16 |
| MERCK SHARP & DOHME CORP. | 6B2S4 | 102,293,969.85 | 102.29 million | 10 |
| SEQIRUS INC. | 7L0Y8 | 81,214,755.78 | 81.21 million | 44 |
| BOEHRINGER INGELHEIM ANIMAL HEALTH FRANCE | FAL37 | 60,357,500.00 | 60.36 million | 17 |
| SANOFI PASTEUR INC. | 7V915 | 60,072,987.54 | 60.07 million | 102 |
Insight
Over the last 5 years, NAICS 325414 obligations totaled $21.39 billion across 4,194 awards, with a high average award value of $5.10 million. The vendor base is highly concentrated: Pfizer Inc. accounted for $13.25 billion, and Regeneron Pharmaceuticals, Inc. added $5.57 billion, together representing nearly 88% of total obligations. The remaining top vendors each received less than $800 million, indicating a steep drop-off after the first two firms despite several vendors with relatively higher award counts, such as Sanofi Pasteur Inc. (102 awards) and Seqirus Inc. (44 awards).
Annual Trend
SELECT
year,
total_obligated,
award_count,
formatReadableQuantity(total_obligated) AS total_obligated_readable
FROM
(
SELECT
toYear(parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate)) AS year,
sum(content__award__dollarValues__obligatedAmount) AS total_obligated,
count() AS award_count
FROM fpds.data
WHERE
contract_type = 1
AND content__award__productOrServiceInformation__principalNAICSCode = '325414'
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) >= toStartOfYear(now()) - INTERVAL 5 YEAR
AND parseDateTimeBestEffortOrNull(content__award__relevantContractDates__signedDate) < toStartOfYear(now())
GROUP BY year
)
ORDER BY year DESC| Year | Total Obligated | Readable | Award Actions |
|---|---|---|---|
| 2025 | -7,549,242.46 | -7.55 million | 491 |
| 2024 | 918,887,389.17 | 918.89 million | 811 |
| 2023 | 307,512,762.42 | 307.51 million | 830 |
| 2022 | -281,571,030.07 | -281.57 million | 1,008 |
| 2021 | 20,447,867,572.99 | 20.45 billion | 1,054 |
Insight
NAICS 325414 shows a highly concentrated five-year obligation profile, with 2021 accounting for the vast majority of the period total at $20.45 billion out of $21.39 billion overall. Obligations then declined sharply in 2022 to -$281.57 million, recovered to $307.51 million in 2023, and increased to $918.89 million in 2024, before turning slightly negative in 2025 at -$7.55 million. Award volume was more evenly distributed than dollars, ranging from 491 awards in 2025 to 1,054 in 2021, with a five-year total of 4,194 awards and an average award value of $5.10 million.
Use FPDS Query for deeper industry analysis
Explore federal procurement data with custom SQL, fast filtering, and deeper industry analysis across agencies, vendors, and annual trends.
Continue from this last 5 years view into full FPDS Query workflows with deeper filtering, custom SQL, saved queries, and broader market comparison.